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Veterinary Biotechnology

Brief Introduction

Shanghai Key Laboratory of Veterinary Biotechnology (ShKLVB) was founded in 1990. Over the past decade ShKLVB has made a series of achievements in the anti-rabbit hemorrhagic fever virus, foot and mouth disease virus, parvovirus, swine transmissible gastroenteritis virus, chicken infectious bursal disease virus, and infectious bronchitis virus. It has made significant contributions to the research on the application and preparation of monoclonal antibodies. Since the establishment of the ShKLVB, she has obtained 40 million yuan financial support from national and local sources, twelve prizes for provincial /ministerial science and technology advancement, and has published more than 450 papers in national and international journals.


Members

  • Director
  • Pan Yuchun

  • Director of Academic Committee
  • Zeng Yitao

  • Team Members
  • Sun Jianhe, Hua Xiuguo, Pan Yuchun, Yu Yan, Xu Jianxiong


    Research Fields

  • Veterinary Microbiology
  • Animal Infectious Diseases
  • Genetics and Breeding
  • Reproduction and Development
  • Nutrition and Feed

  • Research Achievements

  • Sequence and phylogenetic analysis were used to study the HEV infection status in general human population and swine groups in central China. The result indicated that although all the HEV strains prevalent in central China belonged to genotype 4, the strains prevalent in swine were genetically different from those prevalent in the human, which suggested that cross-species transmission of HEV between human and swine might not exist in this area.
  • The bioinformatics approaches were used to explore the reason of conserved forkhead domain and the functional diversity from a phylogenetic perspective within the FoxO family in vertebrates. The result suggested that gene duplication events lead to the formation of four gene lineages. Repeating dN/dS analysis demonstrated that episodic positive selection or relaxed selective constraints has shaped the functional divergence of the FoxO proteins. However, purifying selection appears to be the main influence on the evolution of this family. These findings can serve as useful guidelines to further research on their structure and function, and could offer some help and guidelines for marker assisted selection (MAS) in breeding and transgenic research.

  • Cooperation

  • Shanghai Xiangxin Livestock Poultry co, ltd.
  •   In cooperation with Xiangxin, a set of repeatable combination of breeds (Duroc, Landrace, and Large White) has been selected to achieve significantly increase the genetic progress.

  • Shanghai Songjiang Swine Breeder Test Station
  •   We tested the combining ability of 132 triplet pigs. The aviary weight per pig gained and food intake were recorded through Osborne automatic feeding system. Forty-four pigs were slaughtered for genetic evaluation and data analysis.

    Veterinary Biotechnology

    Shanghai Xiangxin Livestock Poultry co, ltd.

    Veterinary Biotechnology

    Shanghai Xiangxin Livestock Poultry co, ltd.

    Veterinary Biotechnology

    Shanghai Songjiang Swine Breeder Test Station

    Veterinary Biotechnology

    Shanghai Songjiang Swine Breeder Test Station