Gastric cancer is one of the most common malignant tumors in China. The clinical symptom of early gastric cancer is not obvious. However, most gastric cancers have been in advanced when found, and not suitable for operation. As a result, it is imminent to establish a convenient and effective method to detect gastric cancer.
The research group of Professor Cui Daxiang of Shanghai Jiao Tong University (STTU) analyzed a large number of breath samples and filtered 14 volatile organic compounds from them as gastric cancer markers, which can be used to separate patients with early gastric cancer or advanced gastric cancer from healthy people. On this basis, the research group developed a clean, easily prepared Surface enhanced Raman scattering (SERS) sensor to selectively adsorb and detect these markers.
This work has great clinical transformation potential in preliminary screening and stage measurement of gastric cancer. Related works are published in ACS Nano（DOI: 10.1021/acsnano.6b01441, IF=13.334）. Doctoral student Chen Yunsheng is the first author of the paper.
Translated by Wang Jiayu Reviewed by Lu Siyu