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[SJTU Wisdom] SJTU Team Achieves Innovative Breakthrough in TNF-α Vaccines

October 26, 2016      Author: Zhang Li

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Recently, team led by Professor Li Rongxiu from State  Key Laboratory of Microbial Metabolism and the School of Life Science and Biotechnology of Shanghai Jiao Tong University(SJTU) has achieved breakthrough in the studying of TNF-α vaccines.

The research findings were published on the Plos one titled as "A Rationally Designed TNF-α Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice". It was also reported on the Research highlight collum of Nature review rheumatology, a famous journal in immunity of rheumatism, titled as "Paving the way for TNF vaccines".The research team is currently carrying out the preclinical studies and hopes to enter clinical phase as soon as possible.

Link:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033357/Nature review rheumatology article

          http://www.nature.com/nrrheum/journal/vaop/ncurrent/full/nrrheum.2016.171.html 


Translated by Zheng Mengyan  Reviewed by Lu Siyu