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Rational Design of Chiral Brønsted Acid Catalysts Based on Acid-Base Combination Chemistry

Speaker: Prof. Kazuaki Ishihara
When: 15:30, April 27, 2017
Where: Room 518 at Chemistry Building A

Speaker biography:

Professor Kazuaki Ishihara FRSC Laboratory of Catalysis in Organic Synthesis;Research Group of Molecular Chemistry;Department of Molecular and Macromolecular Chemistry;Graduate School of Engineering, Nagoya University B2-3(611), Furo-cho, Chikusa, Nagoya 464-8603, Japan Phone: +81-52-789-3331; Fax: +81-52-789-3222 https://www.ishihara-lab.net Education: 1982-1986 Bachelor of Engineering (under the supervision of Professor Hisashi Yamamoto), Department of Applied Chemistry, School of Engineering, Nagoya University 1986-1988 Master of Engineering (under the supervision of Professor Hisashi Yamamoto), Department of Applied Chemistry, Graduate School of Engineering, Nagoya University 1988-1991 Doctor of Engineering (under the supervision of Professor Hisashi Yamamoto), Department of Applied Chemistry, Graduate School of Engineering, Nagoya University Thesis Title: “Studies on Stereoselective Reactions of Acetals” [Visiting scholar under the supervision of Professor Clayton H. Heathcock at Deaprtment of Chemistry, University of Berkeley, California, USA for three months in 1987.] Positions Held: 1991-1992 Postdoctoral Fellow under the supervision of Professor E. J. Corey at Department of Chemistry, Harvard University, Cambridge, Massachusetts, USA 1992-1994 Assistant Professor, Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Japan 1994-1997 Assistant Professor, Department of Biotechnology, Graduate School of Engineering, Nagoya University, Japan 1997-2001 Associate Professor, Research Center of Waste and Emission Management, Nagoya University, Japan 2001-2002 Associate Professor, Department of Biotechnology, Graduate School of Engineering, Nagoya University, Japan 2002-present Full Professor, Department of Biotechnology, Graduate School of Engineering, Nagoya University, Japan Representative Papers: (1) “Direct condensation of carboxylic acids with alcohols catalyzed by hafnium(IV) salts” Kazuaki Ishihara, Suguru Ohara, Hisashi Yamamoto Science 2000, 290(5494), 1140-1142. DOI: 10.1126/science.290.5494.1140 (Nov.10) (2) “Enantioselective halocyclization of polyprenoids induced by nucleophilic phosphoramidites” Akira Sakakura, Atsushi Ukai, Kazuaki Ishihara Nature 2007, 455(7130), 900-903. DOI: 10.1038/nature05553 (Feb.22) (3) “Quaternary ammonium (hypo)iodite catalysis for enantioselective oxidative cycloetherification” Muhammet Uyanik, Hiroaki Okamoto, Takeshi Yasui, Kazuaki Ishihara Science 2010, 328(5984), 1376-1379. DOI: 10.1126/science.1188217 (Jun.11) (4) “High-turnover hypoiodite catalysis for asymmetric synthesis of tocopherols” Muhammet Uyanik, Hiroki Hayashi, Kazuaki Ishihara Science 2014, 345(6194), 291-294. DOI: 10.1126/science.1254976 (July 18)